Nystatin

Tystatin Oral Suspension contains 100,000 units/mL of nystatin, a polyene antifungal medication specifically formulated to treat fungal infections in the mouth and throat, including oral thrush (oropharyngeal candidiasis). Nystatin works by binding to ergosterol, an essential component of fungal cell membranes, disrupting membrane integrity and causing the fungal cells to break down. Unlike systemic antifungals, nystatin acts locally within the oral cavity, preventing significant absorption into the bloodstream and reducing the risk of systemic side effects.

This medication is particularly effective against Candida species, the most common cause of oral thrush. It is frequently prescribed for individuals with weakened immune systems, such as infants, the elderly, and patients undergoing chemotherapy or immunosuppressive treatments. People with conditions like HIV/AIDS or diabetes, who are at higher risk for fungal infections, may also benefit from nystatin as part of their oral health regimen.

Nystatin oral solution is easy to use: patients typically swish it around their mouth before swallowing or spitting it out, depending on the infection’s severity and location. This ensures targeted, direct contact with the affected areas for optimal treatment results. The medication is generally well-tolerated, with minimal side effects, such as mild nausea, stomach upset, or an unpleasant taste. Serious adverse reactions are rare due to nystatin’s limited systemic absorption, making it a safer option compared to systemic antifungals, which may pose a higher risk of liver toxicity or drug interactions.

Nystatin oral solution can also be used preventively in patients at high risk for developing oral fungal infections. Its localized action, ease of use, and established efficacy make Tystatin Oral Suspension a preferred treatment choice for managing oral and esophageal candidiasis.